Madonna will be performing at the MTV Video Music Awards for the first time since her iconic 2003 set where she kissed Britney Spears and Christina Aguilera. She will open the 2026 ceremony with music from her new album, Confessions II, which has earned her 11 VMA nominations. Jennifer Lopez revealed that she was initially asked to participate in the 2003 performance but couldn't due to filming commitments. Madonna's upcoming performance adds to her legacy of memorable VMA moments, including her 1984 performance of "Like a Virgin." The 2026 VMAs will be hosted by Snoop Dogg and air on CBS, MTV, and Paramount+ on September 27.